How To Use

There are two ways in: Search, when you know what you are looking for, and Browse, when you want to see what the database holds.

Search

  1. Open Search and type in any of the boxes: the compound name, the plant (species or family) or the virus (as printed in the paper, or its ICTV species or family). Tick one or more endpoints (IC50, EC50, IC90, EC90, ED50) to narrow the result. Boxes you leave empty are ignored.
  2. Press Search. The table lists the matching records. Click a column heading to sort, and use Previous and Next to move through the pages.
  3. Open Advanced search to look up a structure by its InChIKey (the full key or its first 14 characters), to limit the value in nM from and to, or to change the number of rows per page.
  4. Click a record number (for example R0018) to open the full record.

The nM limits leave out records whose value is in mass units and could not be converted to nM, because the molecular weight of the structure was not known.

Browse

  1. Open Browse and choose a tab: Virus (grouped by ICTV family), Plant (grouped by plant family), Compound (one entry per structure) or Endpoint.
  2. Open a group to see its entries, or type in Filter this list to find a name quickly.
  3. Click a name to see all of its records in the search table.

Reading a record

A record is arranged in cards. Potency gives the endpoint, the value and unit as printed in the paper, and the same value in nM. Compound gives the name as printed and the structure that was matched to it (InChIKey, SMILES, PubChem number). Plant gives the source plant and its taxonomy. Virus and assay gives the virus as printed with its ICTV species and family, the assay type and the cell line. Cytotoxicity appears when the paper reports a CC50-type value. Source gives the paper, with a link to it.

A field is shown only when the record has a value for it. Structures are matched to compound names by database lookup and were not checked by hand; read the paper when a structure matters to you.

Statistics

The Statistics page shows how the records are spread over endpoints, assay types, virus hosts, virus families and plant families.